Andrew Holding

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methicillin‐resistant
staphylococcus aureus
or MRSA

Welcome

Dr Andrew Holding is a Research Associate at the Cancer Research UK's Cambridge Institute.

Andrew started studying chemistry at the University of Oxford before he went on to apply these skills to investigate how life works at a molecular level. During his PhD at the University of Cambridge he focused on how nature makes the antibiotics we use to treat antibiotic resitant infections including MRSA. In 2009 he moved to the MRC Laboratory of Molecular Biology as a Career Development Fellow investigating how the machinery within the cells interacts to undertake basic processes including the replication of DNA. In 2013 Andrew moved to the Cambridge Institute to focus on the molecular processes that drive breast cancer.

Current Research

Andrew is currently based at Cancer Research UK's Cambridge Institute. His research focuses on the role of the oestrogen receptors (ER) in breast cancer. In 70% of all breast cancer cases this receptor drives the growth and proliferation of the tumour, and is a key target for the drug Tamoxifen. He hopes to provide key insights into how the signalling within the cell dynamically regulates the ER.

For more information about his current and previous work, please go to the Research section of this site.



On–stage at
the Bloomsbury Theatre

Public Engagment

Andrew has worked on many science outreach and public engagement projects including founding and organising Skeptics in the Pub in Cambridge, which holds monthly talks by various speakers with the aim of highlighting the application of critical thinking and scientific method. Notable speakers include popular non-fiction author Simon Singh, statistician David Speigelhalter and historian Christopher Andrew.

In 2010, he was nominated for a Society of Biology Science Communication award by the MRC and was successful in his application for a Catalyst Award from UnLtd and the HEFCE for Social Entrepreneurship to help fund his work. Then in 2012 his project received further funding from a Wellcome Trust People Award to fund a range of podcasts that support his events.

Media

Andrew has been a guest on the The Naked Scientists Q&A radio show as Dr Andy, answering the public's questions on science. He produces and hosts a local radio show on CamFM on Sunday evenings that covers the science behind movies, books and TV shows with a selection of music that relates to the discussions, and has been interviewed by BBC Radio 5 Live's 5 Live Drive and BBC Cambridgeshire on topical science stories.

He has worked with the BBC on several shows as part of a British Science Assocation Media Fellowship, including Horizon and The One Show and written for The Guardian's 'Comment is Free' section along with BlueSci magazine. In 2013 he presented his first show for the BBC World Service called ''What if ... we could all become Cyborgs'.

Public Speaking

Andrew has spoken at schools across Cambridgeshire and the UK, and given talks for interested groups and Science Festivals both localy and internationally. Organisations that have invited Andrew to speak include the The Royal Institution in London. His talks focus on looking at relevant science to today's world and draw on examples in history to see what we can learn. More details can be found on the public engagment page of this site.


Other Activities

Artistic

In his spare time, Andrew has written and acted in several performances put on by the Cambridge University Light Enterainment Society and Two Shades of Blue. One of the most prominent of these was "The Matrix: The Pantomime", which was taken to the Fringe Festival in Edinburgh in 2007 and became a sell-out show. Feel free to download the scripts of either The Matrix: The Pantomime or Treasure Island. He continues to take part in such events; for example, in 2010 he acted in the annual Christmas skit at the MRC Laboratory of Molecular Biology. He has also participated in Bright Club in London and Cambridge and Festival of the Spoken Nerd, both of which focus on the communication of science throught comedy.

Community

Co-founder, part-time administrator and sometime contributor of The Open Guide to Cambridge. The guide is a wiki-based project and allows anyone who visits or knows about the city to contribute information about and their opinions on various places of interest to the site.

He is a volunteer with the Cambridgeshire branch of the British Science Association, trying to help promote science around the county, speaking at events and designing experiments for the public.

He is also a qualified first-aider at work and until recently a volunteer at Addenbrooke's Hospital, but has taken a break since the birth of his second child.


Social Networking


Contact

If you wish to contact me, please feel free to do so with the following address: A....@evath.net. Simply click on the missing part of the e-mail address and follow the instructions to reveal it.